Not with Skype version 8.60 (May 2020) and later.
Skype does not allow the possibility to load any 3rd party virtual driver, which includes the wireless A/V driver of Huddle Hub.
Workaround 1 (launch Skype version 8.59)
Download Skype 8.59 from here:
Make sure to double-click the Skype icon to open it, without drag-and-dropping it to the App folder. This will prevent automatic updates to the new version.
Workaround 2 (remove code signature from Skype)
Proceed as follows:
- close Skype
- open the system Terminal (App -> Utilities)
- paste the following instruction in the Terminal and execute it:
codesign --remove-signature "/Applications/Skype.app/Contents/Frameworks/Skype Helper (Renderer).app"
- open Skype