Not with Skype version 8.60 (May 2020) and later.

Skype does not allow the possibility to load any 3rd party virtual driver, which includes the wireless A/V driver of Huddle Hub.



Workaround 1 (launch Skype version 8.59)


Download Skype 8.59 from here:

https://download.skype.com/s4l/download/mac/Skype-8.59.0.77.dmg


Make sure to double-click the Skype icon to open it, without drag-and-dropping it to the App folder. This will prevent automatic updates to the new version.



Workaround 2 (remove code signature from Skype)


Proceed as follows:


- close Skype

- open the system Terminal (App -> Utilities)

- paste the following instruction in the Terminal and execute it:

codesign --remove-signature "/Applications/Skype.app/Contents/Frameworks/Skype Helper (Renderer).app"

- open Skype